From production to disposal, plastics wreak havoc on human, plant, and animal health and cause immense amounts of waste in our ecosystems, clogging our land, air, and waterways. Plastic pollution in particular poses a serious threat to all life on Earth because of the toxic nature of the chemical additives used during the production process. Recent research reveals plastics are able to enter into the human bloodstream, permanently residing in our bodies until the day we die. 

Plastics are a pervasive and dangerous issue, likely hitting us harder than climate change ever will. If we do not figure out solutions, or the severity of the issue, life as we know it faces an impending deathly threat. To tackle these challenges, we must first understand how plastic harms human health.

How are plastics detrimental to human health? 

Did you know the most commonly used plastic products carry toxic chemicals easily inhaled and ingested by humans? In fact, the incineration of plastic waste in the disposal stage disperses these chemicals into the air and causes the contamination of water and soil, lethal to all people who inevitably come in contact with it.

Every time someone litters at the beach or fails to dispose of their waste properly, they contribute to the spread of toxic chemicals into the environment. This is because ocean waves and radiation from the sun break down plastics such as water bottles, producing microplastics. Microplastics float around in the environment, carrying chemicals used in plastic production along with them and end up being consumed by people through food, water, and breathing them from air. 

Studies have shown microplastics significantly damage cells in the human body, leading to serious health effects, including cancers, lung disease, and birth defects. Not only this, but toxic chemical additives in plastics can alter hormone activity in the human body which disrupts reproduction, growth and cognitive function. Microplastics also act as vessels for pathogens to enter the human body which increases the spread of disease.

Plastics production is hazardous to human health and contributes to greenhouse gas emissions, marking plastics as a significant aspect of the fight against climate change. In fact, in 2022 the global cost of plastic-related health effects was estimated at a staggering $100bn per year.

Who is most affected by plastic in the environment?

Can you imagine knowing the air you breathe everyday is invading your body? This is a reality for residents of “Cancer Alley” in Louisiana where plastics plants along the lower Mississippi River have contributed to the highest rates of cancer in the United States amongst marginalized communities. We must recognize how the dangers of plastics for human health are also an issue of human rights and environmental injustice, as the question of who experiences these health effects the most is connected to where you live and the air you breathe.

Children and infants in the womb are most vulnerable to the harmful effects of plastics due to the early stages of human development being particularly sensitive to hazardous chemicals in the environment. Exposure to plastics has been found to increase the risks of birth complications, lung growth and childhood cancer. Crucially, this means plastic pollution will continue to wreak havoc on our lives and earth for generations to come.

The United States is one of the top contributors of plastic waste globally. The impacts of plastics on human health are particularly concerning due to the difficulty of removing plastic from the environment once they have entered ecosystems. 

By signing the petition calling for the US to join the Global Plastics Treaty, you can help ensure the White House commits once and for all to end the production and sale of single-use plastics by 2030, introduce measures to combat plastic pollution by regulating the entire life cycle of plastic, and requiring producers and retailers of plastics to be liable for the cost of any environmental or health-related damages. Join the fight to End Plastic Pollution and together we will make a difference in raising awareness and reducing the impact of plastics on human health.

Plastic and Human Health: A Lifecycle Approach to Plastic Pollution

Despite being one of the most pervasive materials on the planet, plastic and its impact on human health remain poorly understood. Yet exposure to plastic is expanding into new areas of the environment and food chain as existing plastic products fragment into smaller particles and concentrate toxic chemicals. As plastic production increases, this exposure will only grow.

Research into the human health impacts of plastic must recognize that significant, complex, and intersecting human health impacts occur at every stage of the plastic lifecycle: from wellhead to refinery, from store shelves to human bodies, and from waste management to ongoing impacts as air, water, and soil pollution.

Together, the lifecycle impacts of plastic paint a clear and troubling picture: plastic threatens human health on a global scale. Reducing those threats will demand stopping and reversing the growth in plastics production, use, and disposal worldwide.

To address the human health crisis hiding in plain sight, we must:

Take a lifecycle approach to plastic. The narrow approaches to assessing and addressing plastic impacts to date are inadequate and inappropriate. Making informed decisions that address plastic risks demands a full lifecycle approach to understand the full scope of its toxic impacts on human health. It is also required to ensure that yet more and increasingly complex environmental problems are not created in the attempt to address this one.

Account for distinct risks to human health at every stage of plastic’s lifecycle, from both exposure to plastic particles themselves and associated chemicals. The majority of people worldwide are exposed at multiple stages of this lifecycle:

Extraction and Transport
99% of plastic comes from fossil fuels. The extraction of oil and gas, particularly hydraulic fracturing for natural gas, releases an array of toxic substances into the air and water, often in significant volumes. Over 170 fracking chemicals that are used to produce the main feedstocks for plastic have known human health impacts, including cancer, neurological, reproductive, and developmental toxicity, impairment of the immune system, and more. These toxins have direct and documented impacts on skin, eyes, and other sensory organs, the respiratory, nervous, and gastrointestinal systems, liver, and brain.

Refining and Manufacture
Transforming fossil fuel into plastic resins and additives releases carcinogenic and other highly toxic substances into the air. Documented effects of exposure to these substances include impairment of the nervous system, reproductive and developmental problems, cancer, leukemia, and genetic impacts like low birth weight. Industry workers and communities neighboring refining facilities are at greatest risk and face both chronic and acute exposures during uncontrolled releases and emergencies.

Consumer Products and Packaging
Use of plastic products leads to ingestion and/or inhalation of large amounts of both microplastic particles and hundreds of toxic substances with known or suspected carcinogenic, developmental, or endocrine-disrupting impacts.

Waste Management
All plastic waste management technologies (including incineration, co-incineration, gasification, and pyrolysis) result in the release of toxic metals, such as lead and mercury, organic substances (dioxins and furans), acid gases, and other toxic substances to the air, water, and soils. All such technologies lead to direct and indirect exposure to toxic substances for workers and nearby communities, including through inhalation of contaminated air, direct contact with contaminated soil or water, and ingestion of foods that were grown in an environment polluted with these substances. Toxins from emissions, fly ash, and slag in a burn pile can travel long distances and deposit in soil and water, eventually entering human bodies after being accumulated in the tissues of plants and animals.

Plastic in the Environment
Once plastic reaches the environment in the form of macro- or microplastics, it contaminates and accumulates in food chains through agricultural soils, terrestrial and aquatic food chains, and the water supply. This environmental plastic can easily leach toxic additives or concentrate toxins already in the environment, making them bioavailable again for direct or indirect human exposure. As plastic particles degrade, new surface areas are exposed, allowing continued leaching of additives from the core to the surface of the particle in the environment and the human body. Microplastics entering the human body via direct exposures through ingestion or inhalation can lead to an array of health impacts, including inflammation, genotoxicity, oxidative stress, apoptosis, and necrosis, which are linked to an array of negative health outcomes including cancer, cardiovascular diseases, inflammatory bowel disease, diabetes, rheumatoid arthritis, chronic inflammation, auto-immune conditions, neuro-degenerative diseases, and stroke.

Be aware of and work to end the uncertainties and knowledge gaps that undermine the full evaluation of both acute and long-term health risks at all stages of the plastic lifecycle, and limit the ability of consumers, communities, and regulators to make informed choices.

• Lack of transparency of the chemicals in plastic and its production processes prevents a full assessment of its impacts, reduces the ability of regulators to develop adequate safeguards; consumers to make informed choices; and fenceline communities to limit their exposure.
• Further research is urgently needed to: evaluate intersecting exposures, synergistic effects, and cumulative impacts of the mixtures of thousands of chemicals used in consumer goods; understand the potential transfer of microplastics and associated toxic chemicals to crops and animals; and understand the toxic impacts of microfibers and other plastic microparticles increasingly documented in human tissues.

Embrace a variety of solutions and options to reduce toxic exposure to plastic because plastic has a complex lifecycle with a diverse universe of actors.

• At every stage of the plastic lifecycle and across those stages, solutions should be guided by respect for human health and the right to a healthy environment. Despite remaining uncertainties, existing information about the severe health impacts of the plastic lifecycle justifies the application of a strong precautionary approach to the lifecycle of plastic and the overall reduction of plastic production and uses.
• Health impact assessments that focus solely on the plastic components of products while ignoring thousands of additives and their behavior at every stage of the plastic lifecycle are incomplete.
• Addressing plastic pollution requires adapting and adopting legal frameworks to ensure access to information regarding the petrochemical substances in products and processes, as well as increased independent research to fill existing and future knowledge gaps.
• Solutions must be built on transparency, participation, and the right to remedy. Transparency is required to identify the nature and breadth of exposure to toxic material, as well to assess possible health and environ- mental impacts of technologies touted as “solutions,” such as incineration and plastic-to-fuel technologies.
• Solutions must integrate the right to meaningful participation in decision-making about plastic-related risks, and access to justice when harms arise.
• Measures that succeed at a local level or with respect to a single product stream are often undermined or offset by the emergence of new plastic, new additives, and new exposure pathways that are interwoven in supply chains that cross and recross borders, continents, and oceans. Until we confront the impacts of the full plastic lifecycle, the current piecemeal approach to addressing the plastic pollution crisis will not succeed.

Our groundbreaking report Plastic & Health: The Hidden Costs of a Plastic Planet with Earthworks, GAIA, Healthy Babies Bright Futures, IPEN, Texas Environmental Justice Advocacy Services (t.e.j.a.s.), University of Exeter, and UPSTREAM presents a clear conclusion: even with the limited data available, the health impacts of plastic throughout its lifecycle are overwhelming. Many actions and solutions are needed to confront this threat to human life and human rights. To be effective, they must ultimately reduce the production, use, and disposal of plastic and associated toxic chemicals.